Xu Laboratory
Bridging structural biology and epigenetic regulation.
Saint Louis University School of Medicine
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The laboratory of Dr. Tinghai Xu is dedicated to investigating the complex crosstalk between epigenetic mechanisms including DNA methylation, histone modification, and chromatin remodeling, and their pivotal role in disease pathogenesis. In addition, my laboratory is actively interested in exploring chromatin-related protein complexes.
Our favorite topics are:
DNA Methyltransferase and Nucleosome Complexes
Remodeler-Mediated DNA Methylation on Chromatin
Chromatin-Associated Protein Complexes
GPCR complex drug discoveries
A great way to start 2026 — excited that our cover design idea was accepted for the first issue of Nature Structural & Molecular Biology!
Grateful for the wonderful collaboration with the team!!!
Jan, 2026
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